Human antibody 10E8 targets the conserved membrane proximal external region (MPER) of envelope glycoprotein (Env) subunit gp41 and neutralizes HIV-1 with exceptional potency.Remarkably, ultrastar dc hc550 HIV-1 containing mutations that reportedly knockout 10E8 binding to linear MPER peptides are partially neutralized by 10E8, producing a local pla
Mapping GLAMs: creating a national dataset of GLAMs to develop a categorical climate-change risk assessment scale
Introduction.The PROTECCT-GLAM nef rune project aims to assess and address climate risks for U.S.galleries, libraries, archives, and museums (GLAMs).The project team began with creating a national dataset of GLAMs.Method.The project team used existing datasets that required different auditing and manipulation techniques to align its data.Following
Macroscopic detection of demyelinated lesions in mouse PNS with neutral red dye
Abstract Lysophosphatidylcholine (LPC)-induced demyelination is a versatile animal model that is frequently used to identify and examine molecular pathways of demyelination and remyelination in the central (CNS) and peripheral nervous system snoop snacks (PNS).However, identification of focally demyelinated lesion had been difficult and usually req
Diagnostic Performance of Xpert MTB/RIF Ultra Compared with Predecessor Test, Xpert MTB/RIF, in a Low TB Incidence Setting: a Retrospective Service Evaluation
ABSTRACT The aim of this study was to evaluate the performance of Xpert MTB/RIF Ultra (Ultra) compared with its predecessor, Xpert MTB/RIF (Xpert), in the diagnosis of tuberculosis (TB) in a low TB incidence country.Retrospective analysis was performed on 689 clinical samples received between 2015 and 2018, on which Xpert was performed, and on 715